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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinopathy of prematurity (ROP)
ncRNA name HIF-1α siRNA
ncRNA Category siRNA
Disease name retinopathy of prematurity (ROP)
Species Mus musculus
Tissues/Cell_line retinas
Methods siRNA injection, Western blot, angiography
Expression pattern associated
Functional description The development of retinal neovascularization of ROP can be markedly inhibited by RNA interference targeting HIF-1α.
PubMed ID 21849124
Year 2011
Title HIF-1α siRNA reduces retinal neovascularization in a mouse model of retinopathy of prematurity.
Drug-related ncRNA NO

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